Ingénieur(e) Mécanique/Mécatronique (80 – 100%)

A propos de BionomousBionomous est une spin-off du Laboratoire de Biorobotique de l’Ecole Polytechnique Fédérale de Lausanne, en Suisse. Notre équipe travaille sur le développement et la commercialisation de machines pour automatiser certains procédés en biologie et en biotechnologie, dans le but de faciliter et d’accélérer la recherche dans certains domaines comme la génétique, la toxicologie, la biologie du développement et pour des tests non-cliniques.Votre missionTravailler au sein d’une Start-up suisse en expansion sur le développement d’outils permettant d’augmenter l’efficacité de la recherche en Science de la Vie. La/le candidat(e)…

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Precise spatiotemporal genome editing in Zebrafish using CRISPR/Cas9

Since 1901, Nobel Prizes have been awarded to “those who, during the preceding year, have conferred the greatest benefit to humankind”, in Alfred Nobel’s words1. Last year, Emmanuelle Charpentier and Jennifer Doudna were awarded with this recognized prize in the field of chemistry for their contributions to the genetic engineering tool known as CRISPR/Cas92.CRISPR/Cas9 has been extensively studied and meticulously developed during these last years for efficient and precise genome editing. In this article, we will review the scientific paper: Spatiotemporal Control of CRISPR/Cas9 Function in Cells and Zebrafish using…

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Startup Days 2021

Bionomous' participated at the Startup Days 2021 (SUD21) in Bern Last week, Bionomous team had the pleasure to attend the Startup Days in Bern, and pitch in front of a large audience. The Start-up days was a selected COVID-19 pilot event, with 600 attendees.  Besides, during the Startup Days, we also had the great opportunity to participate in an active exchange with politicians and representatives of the Swiss administration about the start-up ecosystem in the country and the impact of politic actions on the development of disruptive technologies. Frank Bonnet,…

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Software developer internship (80 – 100%)

About Bionomous Bionomous is a spin-off from the Biorobotics Laboratory at the Ecole Polytechnique Fédérale de Lausanne, in Switzerland. Our team works on the development and commercialization of devices that automatize processes in biology and biotechnology, to accelerate research in fields such as genetics, toxicology, development and behavioral biology, and non-clinical studies. Your mission Work within an EPFL spin-off at the Innovation Park on the development, testing and deployment of software tools for our new product. The candidate will produce, maintain and document Android application that are used to control…

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Zebrafish as a model to study the toxicity of different pesticides – a case study

Since 1974, World Environment Day has been celebrated every year on 5 June, so this month we want to acknowledge this event by reviewing a scientific article where zebrafish are used to test the toxicity of certain pesticides: Toxicity of Deltamethrin to Zebrafish Gonads Revealed by Cellular Biomarkers 1, published in Journal of Marine Science and Engineering on January 23th, 2020.This article investigates the chronic effects of deltamethrin, a synthetic insecticide extensively used in pest control, on gonads. For doing so, the authors of the mentioned article exposed zebrafish adults…

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Startup days 2021

Bionomous will be present at the Startup days 2021 (SUD21)!Bionomous will attend to the Startup days 2021 organised in Bern on the 22nd and 23rd of June, and will have the pleasure to pitch on the 23rd! We are very proud to be one of the numerous startups found in Switzerland. Born as a spin off from EPFL, we have been able to grow and develop our technology in the amazing hub that Switzerland is for entrepreneurship. Bionomous operates from the swiss region of Vaud in the western part of Switzerland. Western Switzerland…

FutureHealth Basel 2021

Bionomous will be present at FutureHealth Basel 2021!FutureHealth Basel 2021 will be dedicated to the theme "Rethinking Patient Experience". The program will provide insights into practice-relevant topics and will facilitate a solution-oriented dialogue. Its online platform has been designed to promote networking among the participants to explore potential partnerships and collaborations that will improve the healthcare industry. The event will take place on the 27th and 28th of April  and we are thrilled to participate. We are looking forward to exploring new partnerships opportunities that will boost the future of the health care industry.To…

Bio Digital 2021

Bionomous will attend Bio Digital!BIO Digital 2021 has been organised to gather for one week the global biotech industry. It attracted 16,000+ biotechnology and pharma leaders in the past years who highlighted biotech's transformative role and impact on today's challenges.This year, the event will be for the second time set up as a fully digital experience, where participants will come together for intense networking to discover new opportunities and promising partnerships.Thanks to Innosuisse trade fair program, Bionomous will be present in this year's edition from the 14th to the 18th…

Zebrafish to study a broken heart: macrophages’ implication in scar formation after a heart attack

In this series of articles, we review some of the key scientific publications of 2020 which included zebrafish in their studies. This review will cover an article published in Nature Communications on January 30th, 2020: Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair1.This article challenges the current model of scarring after a heart attack and implicates macrophages, a type of white blood cell of the immune system, as direct contributors to collagen deposition during this process.Heart attack and heart failureScarring process after a…

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Man-made chemicals PFAS surround us, and you did not even know about their toxic effect: what zebrafish can tell us

In this series of articles, we review some of the key scientific publications of 2020 which included zebrafish in their studies. This second review will cover an article published in Environmental Health Perspective on April 9th 2020: Evaluation of Developmental Toxicity, Developmental Neurotoxicity, and Tissue Dose in Zebrafish Exposed to GenX and Other PFAS1.In this article, the authors have studied the toxicology of different PFAS, short for poly and perfluoroalkyl substances, which are substances widely present in our daily life.PFAS and concerns about their useGrouping PFAS based on shared toxicity…

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