Xenopus laevis chromosomes in the Christmas spirit

Christmas is coming and even the African clawed frog (Xenopus laevis) cells are in the Christmas spirit. In fact their cells contain a structure that looks like Christmas trees. But what is this particular structure? They are rRNA transcription units in chromatin spreads. And what does this mean? Keep reading to understand it! In this article we will explain the genetic and transcription bases of this structure. DNA and RNA Christmas tree structure  Conclusion References DNA and RNA All living organisms are built from deoxyribonucleotide acid (DNA). In animals, most…

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Where do our aquatic models come from ?

Did you know that the EggSorter works with small biological entities from different species: from zebrafish, medaka and killifish eggs to xenopus oocytes and embryos? Sounds cool, right? But do you know where these species exactly come from and what they are used for in research? This article presents the ecology of these organisms and gives a glimpse of how they are used in research. Zebrafish Medaka Killifish African clawed frog Conclusion References Zebrafish The zebrafish is used as a model organism in laboratories because they are easy to feed…

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Do zebrafish like classical music ?

In laboratories and fish facilities, environmental noise management is essential to ensure the well-being of zebrafish and optimize their reproduction. Noises from the aquarium facility, as well as from human activities, can influence zebrafish behavior. In this article, we talk about how fish react to environmental sounds and how music, especially classical music can positively influence fish behavior and make experiments more reliable. Zebrafish hearing Anthropogenic sound effects on zebrafish Classical music effects on zebrafish Conclusion References  Zebrafish hearing Zebrafish can detect sounds, vibrations and motion through their well-developed auditory…

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How can zebrafish embryos help to find a personalized treatment for leukemia?

September is blood cancer awareness month. Leukemia is the broad term for blood cancer, and just in Switzerland, there are more than 1000 new cases listed per year. It is also the most common childhood cancer (1). The diversity of leukemia and the ineffectiveness of current treatments call for new treatments tailored to each individual, using the patient's own tumor cells. Zebrafish are interesting for personalized medicine due to their similarities with human genetics and physiology. In fact, about 70% of human disease genes have an equivalence in zebrafish (2). …

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Using zebrafish for water quality control

Water pollution is evolving into a serious human and environmental health problem. Numerous pollutants can be found in waters, including synthetic compounds, chemicals naturally present in the environment and endocrine disruptors. To ensure good water quality and safe consumption, drinking water must be certified free of these toxins. An effective and accurate quality control system is therefore essential. Over the past few years, zebrafish have made their way into this field and can now be used as in-vivo water quality control systems. To find out more, read on! Environmental health…

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Women’s contribution to zebrafish science

February 11th marked the 7th International Day of Women and Girls in Science. The purpose of this day is to recognise the role of women in science and to promote full and equal access to science to all women and girls who wish to participate and take part in leading actions and innovations around the world. At Bionomous, we recognise the power and value of women and we have gathered in this article a bit of history of women in science, several contributions of women to research in general, and…

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How zebrafish can help tackle cervical cancer

Cervical cancer is the fourth most common malignancy diagnosed in women and causes 270’000 deaths every year1. In 2008, the Nobel Prize of medicine was awarded to Dr. Herald zur Hausan – a German virologist and medical doctor – for his work and discoveries on HPV causing cervical cancer2. His discoveries led to a worldwide joint effort by virologists, epidemiologists, molecular biologists and clinicians to tackle the disease by preventing viral infection through the development of efficient prophylactic vaccines for HPV3. Vaccines are highly efficient and prevent the majority of…

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Introducing Xenopus!

Over the past couple of weeks, you might have encountered men of all ages, proudly wearing a freshly grown moustache. During the month of November, many men take part in Movember, an annual event which involves growing a moustache to raise awareness around men’s health and in particular men’s mental health and prostate and testicular cancer. World-wide Movember foundations raise money and organise events with the aim of increasing early cancer detection, diagnosis and effective treatments. While raising awareness and increasing early detection may prevent many deaths, a better comprehension…

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Get to know Bionomous: the interview

On November 19th, Bionomous celebrated two years of existence. For this special event, Bionomous’ team has interviewed Frank and Ana, the co-founders of Bionomous, to get a better insight into what it took to bring the EggSorter to life, start a company as well as the projects they have in mind for the future. If you are interested in knowing more about how Bionomous was founded, read on! https://youtu.be/6Qs22R-syBk What is Bionomous? What do you do? Frank: Bionomous is a swiss start-up that was born at the Ecole Polytechnique Fédérale…

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Caudal fin regeneration in zebrafish

Halloween is right around the corner and you will soon be seeing various spooky creatures parading down the streets: ghosts, wizards and zombies which might even be missing a limb. While ghosts and wizards are usually classified as magical creatures, zombies have something in them which make them slightly more real. A zombie is an animated corpse which has been brought back to life and although resurrection remains completely unreal, regenerative medicine has been working on replacing and regenerating defective cells, tissues and organs with the goal of restoring normal function. Some animals…

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