Creativity in zebrafish research

In the USA, January is characterized by creativity. In fact, the creativity month celebrates outside-the-box-thinking, the expression of ourselves and the innovations. To match with this idea, we decided to highlight some original uses of zebrafish and related technologies, for which researchers have had to be creative. Some of them are: the use of zebrafish as environmental sensors, as a model to study microbiome-host interactions, as a tool for personalized medicine, on the possible uses of artificial intelligence, and finally, on a double mutant strain called “casper”.  Zebrafish as environmental…

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Do zebrafish get bored?

November is ending and in this period of late autumn people often have difficulties finding activities to keep them occupied. Rainfall and cold force us to stay at home and without inside activities, we can easily get bored. And what about zebrafish in their tank? Can they also get bored?  This article of the month aims to highlight the importance and impacts of enrichment in fish tanks on zebrafish boredom, anxiety and cognition. Enrichments are also part of the 3R’s (Replacement, Reduction and Refinement) principles.  3R's principles Natural environment of…

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Fluorescent zebrafish and the detection of transgenic lines by the EggSorter

Halloween is just around the corner and zebrafish are in a spooky mood too! Did you know that fish can be fluorescent? Researchers are using fluorescent zebrafish to study a wide range of development mechanisms and pathways. This article explains how fluorescent zebrafish are obtained and how fluorescence can be detected. It also highlights the areas of use and important discoveries made possible by this technology. Finally, the article also explains how the EggSorter can be adapted to detect fluorescence.  Zebrafish transgenic lines Fluorescence detection in the EggSorter Conclusion References…

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Zebrafish to study the effects and impacts of alcohol

Alcohol and alcoholism represents a major concern for public health. Each year, more than 3 million deaths are caused by excessive alcohol consumption (1). Drinking has become a regular part of going out with friends and family. Drinking alcohol not only influences the behaviour of consumers, but also their metabolism, and it is not without any effect on the organism. In order to gain a better understanding of the metabolism and effects of alcohol, numerous studies are being carried out on model organisms. This article presents the effects of alcohol…

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Automating the sorting of Xenopus oocytes and embryos

Xenopus laevis is the scientific name of the African clawed frog. This species is native from southern Africa and inhabits slow moving water or stagnant ponds. Its facility to adapt to different environments and conditions makes it considered as an invasive species in Europe, North America and South America (1). The consequence of its invasiveness is a decrease in the local biodiversity because of the competition with local amphibians and the fact that it eats local fishes and invertebrates (1). On the other hand, X.laevis is a very good model organism…

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Virtual reality to study the zebrafish brain

Virtual reality games are becoming increasingly popular. They allow users to fully immerse themselves in another, virtual world.  Did you know that virtual reality systems are also used in research ? It is the case in the study of the brain and its mechanisms. This article is going to explain how it is possible to track neuronal activities in fish brains, using virtual reality. Studies with zebrafish where virtual reality is involved The method Conclusion References Studies with zebrafish where virtual reality is involved Virtual reality is used to study…

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Perception of seasonality in zebrafish

Summer is here and we can enjoy the long days. Longer days allow us to be more active and can give us more energy. But what about animals? Do they perceive the changing of the seasons? This month we are going to discover how zebrafish perceive environmental changes such as light and temperature. Natural range Monsoon impacts on zebrafish Perception of seasonality Conclusion References Natural range Zebrafish are found in the river Ganges and its branches in India, Bangladesh and Nepal. They can also be found in Sri Lanka and…

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The AquaSorter, a solution to automate the screening and sorting of fish eggs for the aquaculture industry

This month's article will target the amazing news that we received in May! Bionomous was selected to receive the support of Innosuisse in the frame of the Swiss Accelerator. Our project AQUASORTER (Automation and QUAlity SORting Tools for thE aquacultuRe industry) will receive the necessary funding to adapt our current technology for the fish farms industry. Our project focuses on the fish farms industry as there is a need to increase the efficiency of this industry to respond to a  global demand. In fact, aquaculture is expected to provide over…

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Zebrafish as a model in Parkinson’s disease

April is Parkinson disease awareness month and for this reason, we decided to talk about zebrafish and this neurodegenerative disease. By their numerous advantages as a model organism, zebrafish show us one more time that they are relevant in neurotoxicity studies and neurodegenerative disorders. The prevalence of Parkinson disease has increased over the past 25 years (1) and for this reason, studies about the comprehension of this disease are really important to find an effective treatment.  Parkinson disease Zebrafish models of Parkinson's disease Conclusion References Parkinson disease Parkinson disease (PD)…

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Fifth in the series : Prof. Janet Heasman

For the last week of March and as the end of our mini-series, we are pleased to present Prof. Janet Heasman. She has dedicated her career to vertebrate development using Xenopus laevis as a model.  Biography Her contribution to Xenopus science Conclusion References Biography Janet Heasman was born in Hartlepool, England (1,2). She attended University College Hospital Medical School in London and in the second year, she took an intercalated BSc degree in J.Z. Young’s Anatomy department where she met her husband, Christopher Wylie (1,2) . Janet succeeded her BCs…

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