Ingénieur(e) Mécanique/Mécatronique (80 – 100%)

A propos de BionomousBionomous est une spin-off du Laboratoire de Biorobotique de l’Ecole Polytechnique Fédérale de Lausanne, en Suisse. Notre équipe travaille sur le développement et la commercialisation de machines pour automatiser certains procédés en biologie et en biotechnologie, dans le but de faciliter et d’accélérer la recherche dans certains domaines comme la génétique, la toxicologie, la biologie du développement et pour des tests non-cliniques.Votre missionTravailler au sein d’une Start-up suisse en expansion sur le développement d’outils permettant d’augmenter l’efficacité de la recherche en Science de la Vie. La/le candidat(e)…

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Precise spatiotemporal genome editing in Zebrafish using CRISPR/Cas9

Since 1901, Nobel Prizes have been awarded to “those who, during the preceding year, have conferred the greatest benefit to humankind”, in Alfred Nobel’s words1. Last year, Emmanuelle Charpentier and Jennifer Doudna were awarded with this recognized prize in the field of chemistry for their contributions to the genetic engineering tool known as CRISPR/Cas92.CRISPR/Cas9 has been extensively studied and meticulously developed during these last years for efficient and precise genome editing. In this article, we will review the scientific paper: Spatiotemporal Control of CRISPR/Cas9 Function in Cells and Zebrafish using…

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Startup Days 2021

Bionomous' participated at the Startup Days 2021 (SUD21) in Bern Last week, Bionomous team had the pleasure to attend the Startup Days in Bern, and pitch in front of a large audience. The Start-up days was a selected COVID-19 pilot event, with 600 attendees.  Besides, during the Startup Days, we also had the great opportunity to participate in an active exchange with politicians and representatives of the Swiss administration about the start-up ecosystem in the country and the impact of politic actions on the development of disruptive technologies. Frank Bonnet,…

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Software developer internship (80 – 100%)

About Bionomous Bionomous is a spin-off from the Biorobotics Laboratory at the Ecole Polytechnique Fédérale de Lausanne, in Switzerland. Our team works on the development and commercialization of devices that automatize processes in biology and biotechnology, to accelerate research in fields such as genetics, toxicology, development and behavioral biology, and non-clinical studies. Your mission Work within an EPFL spin-off at the Innovation Park on the development, testing and deployment of software tools for our new product. The candidate will produce, maintain and document Android application that are used to control…

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Zebrafish as a model to study the toxicity of different pesticides – a case study

Since 1974, World Environment Day has been celebrated every year on 5 June, so this month we want to acknowledge this event by reviewing a scientific article where zebrafish are used to test the toxicity of certain pesticides: Toxicity of Deltamethrin to Zebrafish Gonads Revealed by Cellular Biomarkers 1, published in Journal of Marine Science and Engineering on January 23th, 2020.This article investigates the chronic effects of deltamethrin, a synthetic insecticide extensively used in pest control, on gonads. For doing so, the authors of the mentioned article exposed zebrafish adults…

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Zebrafish to study a broken heart: macrophages’ implication in scar formation after a heart attack

In this series of articles, we review some of the key scientific publications of 2020 which included zebrafish in their studies. This review will cover an article published in Nature Communications on January 30th, 2020: Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair1.This article challenges the current model of scarring after a heart attack and implicates macrophages, a type of white blood cell of the immune system, as direct contributors to collagen deposition during this process.Heart attack and heart failureScarring process after a…

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Man-made chemicals PFAS surround us, and you did not even know about their toxic effect: what zebrafish can tell us

In this series of articles, we review some of the key scientific publications of 2020 which included zebrafish in their studies. This second review will cover an article published in Environmental Health Perspective on April 9th 2020: Evaluation of Developmental Toxicity, Developmental Neurotoxicity, and Tissue Dose in Zebrafish Exposed to GenX and Other PFAS1.In this article, the authors have studied the toxicology of different PFAS, short for poly and perfluoroalkyl substances, which are substances widely present in our daily life.PFAS and concerns about their useGrouping PFAS based on shared toxicity…

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Bilan magazine selects Bionomous as one of the most promising startups in Switzerland

The magazine Bilan, the leading swiss business magazine has named us one of the most promising and best start-ups in Switzerland! We are very proud to announce that Bionomous has been named one of the best Swiss startups to invest in. Every year, Bilan conducts a search for new start-ups appearing in the Swiss ecosystem (start-ups less than 3 years old) and selects those with the greatest potential. In this 9th edition, 270 start-ups were listed, 88 sent their application and 31 were selected as the most promising ones.  Bilan has been the reference media…

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IMD and Bionomous: collaborating for success

We are so excited to have started the collaboration with the IMD's MBA students ! Last December we won the IMD Startup Competition to participate in a program which provides a unique opportunity to get the insights of participants in IMD’s MBA and Executive MBA programs and work with them. This last month we have started working with the four amazing students with whom we are going to collaborate in the coming months. Thanks to their different areas of expertise: from branding and advertisement to project management and financials, and their enthusiasm and motivation,…

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On déménage!

Our team is growing and we are moving to a new and bigger space! So far, since the beginning of the project we have been working at the Mechanics building of EPFL, generously hosted in the laboratories of Prof. Francesco Mondada, where in fact all the idea of the EggSorter started.  But we have been growing and it is time to move into a bigger space, where we can continue developing our technology. In this way, from February we will be at the EPFL Innovation Park (Bâtiment F), hosted at maxon's offices. maxon…

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