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Read more about the article How can zebrafish embryos help to find a personalized treatment for leukemia?
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How can zebrafish embryos help to find a personalized treatment for leukemia?

September is blood cancer awareness month. Leukemia is the broad term for blood cancer, and just in Switzerland, there are more than 1000 new cases listed per year. It is also the most common childhood cancer (1). The diversity of leukemia and the ineffectiveness of current treatments call for new treatments tailored to each individual, using the patient's own tumor cells. Zebrafish are interesting for personalized medicine due to their similarities with human genetics and physiology. In fact, about 70% of human disease genes have an equivalence in zebrafish (2). …

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13 September 2022
Read more about the article Studying breast cancer with zebrafish: a case study
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Studying breast cancer with zebrafish: a case study

In this new series of articles, we will review some of the key scientific publications of 2020 which included zebrafish in their studies. This first review will cover an article published in Clinical Cancer Research on March 15th 2020: Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein that Promotes TGFβ-induced breast cancer metastasis1.In this article, the authors have focused their research on a subset of proteins involved in the tumour cell intracellular degradation pathway as a potential treatment for breast cancer. To get a full comprehensive overview of the…

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29 March 2021