Using zebrafish for drug testing

Toxicology studies have proven to be quite translatable from zebrafish to mammals. As a matter of fact, concordance between studies ran on zebrafish and rodents can reach up to 87% (1). Therefore, the use of zebrafish in the fields of pharmacology and toxicology is opening new and innovative ways to test and develop new drug compounds and understand underlying disease mechanisms.In this article, we will briefly address the process of drug development and clinical research, ways in which zebrafish are used in the pharmaceutical industries; and the bottlenecks and issues potentially involved.Drug…

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