Advancing 3D Cell Culture with Automation: Organoids, Spheroids and Assembloids
The shift to 3D cell culture, with spheroids, organoids, and assembloids, is opening new doors in biological research, offering models that better mimic human tissues and disease. Yet as these models become more intricate, so do the challenges: ensuring uniformity, establishing reproducible and scalable production, etc. This month, we explore how automation is helping researchers […]
How Automation is Advancing Fish Models in Toxicology
When it comes to toxicology, fish embryo offer something rare: models that are fast, ethically sound, and biologically relevant. But as research scales up, manual workflows can become a bottleneck, limiting both speed and reproducibility. In this month’s article, we explore how automation is changing the game, helping labs unlock the full potential of fish […]
Stronger together: how NAMs can be combined to achieve more predictive results
New Approach Methodologies (NAMs) are increasingly used to study biological effects in more human-relevant and ethical ways, yet each model captures only part of the picture. In this month’s article, we explore how combining complementary NAMs, such as 3D cell cultures (e.g. organoids and spheroids) and zebrafish embryos, can help strengthen interpretation and improve confidence […]
From Manual Handling to Automation: The Future of Zebrafish Embryo Workflows
Handling zebrafish embryos may seem simple, but doing it at scale is often a real challenge. This month’s article explores how workflows are shifting toward automation to support higher throughput, better reproducibility, and streamlined research processes. Introduction Current Workflows in Zebrafish Embryo Research The Role of Automation Applications in Drug Testing, Toxicity & More Conclusions […]
EvoDevo in Zebrafish: Bridging Evolution, Development, and Drug Discovery
Evolutionary Developmental Biology, also known as EvoDevo, explores how developmental processes shape evolutionary change. Zebrafish, with their unique genetic and developmental features, have become a cornerstone for EvoDevo research and a powerful tool for drug discovery and toxicity testing. This article introduces the science behind EvoDevo, the advantages of zebrafish as a model, and how […]
What are zebrafish?
As far as research is concerned, all of us are well aware of the use of Mus musculus (mice) or Drosophila melanogaster (fruit flies) as animal models in laboratories. But what about Danio rerio, also known as zebrafish? Over the past several years, the use of zebrafish as a model in several research areas has increased due to numerous […]