From promise to practice: Why alternatives to animal testing aren’t yet scalable

As described in last month's article, New Approach Methodologies (NAMs) and Non-Animal Technologies (NATs), like organoids or fish eggs, are transforming the landscape of biomedical research, toxicology, and drug development. By offering human-relevant insights while reducing or replacing animal use, they hold the promise of more ethical, predictive, and cost-effective science. So, what's limiting their scalability?IntroductionSample handlingImage analysisData recoveryConclusions & outlooksReferences Introduction Despite rapid advances, many NAMs and NATs remain difficult to scale. This is often due to manual processes, complex protocols, reliance on expert operators, and variability across labs.…

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Towards a future beyond animal testing?

As spring fades into summer and nature bursts into full bloom, it is a fitting time to reflect on scientific approaches that promote innovation while advancing more ethical and sustainable research practices. This past spring was filled with events and initiatives that energized the research community and accelerated the development of forward-thinking solutions. Among them, New Approach Methodologies (NAMs) are emerging as powerful alternatives to traditional animal testing.What are NAMs exactly? How can they effectively be used in research? And what is the vision of regulatory bodies on that matter?…

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