Diane LeDroit - Bionomous

Behind the Tanks: Zebrafish Research Meets Automation

Ever wondered what life looks like inside a zebrafish research facility? From rows of clear tanks to the daily routines of dedicated scientists, these labs are where small fish make a big impact on biomedical discovery. In this exclusive interview, we go behind the tanks with one of our partner facilities to explore how automation is reshaping zebrafish research to make it faster, more reliable, and ready for the challenges of tomorrow.IntroductionInterviewConclusions & outlooksReferences Introduction Zebrafish have become one of the most important model organisms in life sciences, widely used…

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22 September 2025

Articles

How can zebrafish eggs help us understand climate change?

The last decade was the hottest on record, and its consequences go far beyond melting glaciers. Climate change is disrupting ecosystems, threatening food security, and putting human health at risk. To address these complex challenges, scientists need research tools that are not only robust and predictive but also ethical and scalable. That’s where New Approach Methodologies (NAMs) such as zebrafish eggs come into play, offering powerful insights into how a warming world impacts life at every scale. But how can something as small as a fish egg help us tackle…

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18 August 2025

Articles

From promise to practice: Why alternatives to animal testing aren’t yet scalable

As described in last month's article, New Approach Methodologies (NAMs) and Non-Animal Technologies (NATs), like organoids or fish eggs, are transforming the landscape of biomedical research, toxicology, and drug development. By offering human-relevant insights while reducing or replacing animal use, they hold the promise of more ethical, predictive, and cost-effective science. So, what's limiting their scalability?IntroductionSample handlingImage analysisData recoveryConclusions & outlooksReferences Introduction Despite rapid advances, many NAMs and NATs remain difficult to scale. This is often due to manual processes, complex protocols, reliance on expert operators, and variability across labs.…

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28 July 2025

Articles

Towards a future beyond animal testing?

As spring fades into summer and nature bursts into full bloom, it is a fitting time to reflect on scientific approaches that promote innovation while advancing more ethical and sustainable research practices. This past spring was filled with events and initiatives that energized the research community and accelerated the development of forward-thinking solutions. Among them, New Approach Methodologies (NAMs) are emerging as powerful alternatives to traditional animal testing.What are NAMs exactly? How can they effectively be used in research? And what is the vision of regulatory bodies on that matter?…

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30 June 2025