Standardize 3D cell culture workflows from screening to plating

From oncology to toxicology, our AI-powered sorters bring precision and reproducibility to 3D cell culture—screening, sorting, and plating with consistency and care.

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Bring clarity, consistency, and scale to 3D cell culture

Bionomous automates the most variable parts of 3D cell culture—standardizing how you select your 3D cell cultures for downstream assays.

Reduce variability, improve reproducibility

Standardize your selection criteria across experiments, users, and timepoints—ensuring reliable results in every assay.

Accelerate high-content screening

Handle hundreds to thousands of samples per run with precise classification based on size, shape, and marker expression.

Reduce hands-on time in 3D cell culture workflows

Replace manual sorting with intelligent automation—reducing handling errors and allowing scientists to focus on innovation.

Adapt the EggSorter for 3D cell culture-based research

Originally designed for small biological entities like fish embryos, the EggSorter also handles organoids and spheroids, automating how you screen, classify, and plate complex 3D cell structures.

Automate viability selection

Manual sorting often misses subtle signs of damage. The EggSorter isolates and classifies organoids and spheroids with consistent accuracy using morphology, size, and imaging.

Support standardized toxicology studies

Prepare consistent organoid and spheroids populations for compound exposure by filtering out poor-quality samples, enabling reproducible readouts and assays.

Isolate fluorescently labeled organoids

Use built-in fluorescence imaging to select organoids and spheroids with tissue-specific or disease-relevant markers, ideal for high-content screening.

Customize how the EggSorter identifies organoids

LabSwipe makes it easy to create your own sorting models using images from your experiments. Just label what counts as viable and the AI learns to recognize it, no coding or data science required.

Target what matters in your assays

Whether you’re looking for structural integrity, uniform size, or specific morphology, LabSwipe lets you define sorting logic around your priorities.

Refine accuracy with each run

Continue improving your model over time. LabSwipe supports iterative training—adjust as your research evolves without starting from scratch.

Train with your own image sets

You decide what viability looks like. Just label a few representative samples, and the AI learns your criteria automatically.

Trusted by leading
labs

Hear about our impact in labs like yours

At the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), we are using the EggSorter for sorting Nothobranchius furzeri wild type eggs onto plates containing coconut substrate. The EggSorter has proven to be a highly reliable and efficient tool in our workflow, significantly streamlining the egg-sorting process.

 

We are very satisfied with its performance. The system operates with very high precision and consistency, helping us to save time and standardize a previously labor-intensive step. The EggSorter fully meets our expectations and has become an indispensable part of our daily work with N. furzeri embryos

— Beate Hoppe, Facility Manager, Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)

Our goal was to robotize the sorting of the fish eggs to improve our productivity. We acknowledge the perseverance of Bionomous to solve technical difficulties and successfully deliver the tool adapted to our specific needs. The eggsorter dedicated to Medaka fish eggs facilitates the work of our technicians.

— Gregory Lemkine, CEO, Laboratoire Watchfrog S.A.

The Bionomous EggSorter saves me valuable time in the laboratory while ensuring accurate and reliable results.
Thanks to its automation, I can focus on my experiments/other tasks without worrying about repetitive sorting tasks.

Page Lab | Louvain Institute of Biomolecular Science and Technology (LIBST)

Read our FAQs

What sample sizes are supported?

The device works with entities sized 500 µm to 2 mm. To ensure consistent sorting, the batch should have a homogeneity of ±100 µm.

Processes up to 1 entity every 0.5 seconds (depending on mode, up to 5 sec/entity).

On average:

  • 50 entities in a Petri dish → 2–3 minutes
  • 96-well plate → 3–5 minutes

Brightfield imaging (transmitted and reflected light)

Fluorescence screening with up to 6 filter cubes, including:

  • BFP, GFP, YFP, tdTomato, mCherry A, mCherry C


(Full specifications available upon request.)

The minimum dispensing dose is 50 µL per sample, with a precision of ±10%.

The EggSorter is flexible and can dispense into:

  • Falcon tubes (up to 2)
  • Multiwell plates (6x to 96x wells, up to 4 plates)
  • Petri dishes (up to 4 × 10 cm)

It can be cleaned with 70% ethanol or 5–10% bleach, ensuring safe and easy maintenance.

  • 50 × 50 × 30 cm (L × W × H)
  • Weight: ~18 kg