Automate fish embryo workflows for quality and control

For zebrafish, killifish and similar models, our AI-powered sorters bring automation to research using fish models —screening and selecting fish embryos with speed, precision, and care. Supporting New Alternative Methodologies (NAMs) worldwide.

Automate your embryo workflows with clarity and control

Whether you’re advancing developmental biology or scaling tox assays, Bionomous helps you screen, sort, and plate eggs with precision—saving time, reducing variability, and improving outcomes.

Screen more embryos, faster

Handle thousands of embryos per hour with up to 95–99% accuracy—supporting both lab-scale experiments and industrial environments.

Improve fish embryo selection quality

Detect malformations, unfertilized eggs, or marker expression using bright-field and fluorescence imaging—so only viable embryos move forward.

Reduce manual labor and errors

Automate one of the most tedious steps in aquatic biology—freeing up researchers and technicians to focus on analysis, not sorting.

Simplify fish embryo workflows in aquatic research

The EggSorter brings automation to aquatic biology by sorting embryos with speed, accuracy, and minimal disruption. From screening developmental stages to isolating fluorescent markers, it gives you reliable results—every time.

Automate aquatic toxicology workflows

Easily sort embryos by stage and viability to prepare for exposure studies—standardizing early endpoints and improving reproducibility in toxicology assays.

Enhance genetic line selection

Use fluorescence-based sorting to isolate transgenic or reporter-line embryos with high accuracy—reducing false positives and saving downstream effort.

Reduce stress and embryo loss

Gentle handling and low-shear movement preserve embryo viability while removing damaged or unfertilized eggs—ideal for long-term culture or imaging.

Build your own embryo sorting criteria—no code required

LabSwipe lets you define what “viable” means for your application. Whether you’re isolating embryos with transgenic markers or optimizing egg quality, you can create and apply custom AI models with just a few swipes.

Train for species-specific traits

Each species has unique features. Use LabSwipe to annotate images and teach the sorter to recognize embryo traits in zebrafish, medaka, killifish, or similar models.

Customize sorting protocols

Design your own grading logic for morphology, size, or stage. Ideal for different research projects and husbandry protocols.

Update models as needs evolve

Update your model as protocols or production cycles evolve. LabSwipe lets you update and retrain AI models instantly—so you stay in control.

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Which species can the EggSorter handle?

The EggSorter is designed for fish eggs, including:

  • Zebrafish (Danio rerio) eggs (0–40 hpf)
  • Killifish (Nothobranchius furzeri) eggs (0 hpf to hatching)
  • Medaka (Oryzias latipes) eggs (0 hpf to hatching)

The device works with entities sized 500 µm to 2 mm. To ensure consistent sorting, the batch should have a homogeneity of ±100 µm.

Processes up to 1 entity every 0.5 seconds (depending on mode, up to 5 sec/entity).

On average:

  • 50 embryos in a Petri dish → 2–3 minutes
  • 96-well plate → 3–5 minutes

Brightfield imaging (transmitted and reflected light)

Fluorescence screening with up to 6 filter cubes, including:

  • BFP, GFP, YFP, tdTomato, mCherry A, mCherry C

 

(Full specifications available upon request.)

The minimum dispensing dose is 50 µL per sample, with a precision of ±10%.

The EggSorter is flexible and can dispense into:

  • Falcon tubes (up to 2)
  • Multiwell plates (6x to 96x wells, up to 4 plates)
  • Petri dishes (up to 4 × 10 cm)

No. Studies show that embryos remain healthy after processing with the EggSorter:

It can be cleaned with 70% ethanol or 5–10% bleach, ensuring safe and easy maintenance.

  • 50 × 50 × 30 cm (L × W × H)
  • Weight: ~18 kg

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