Zebrafish to study a broken heart: macrophages’ implication in scar formation after a heart attack

In this series of articles, we review some of the key scientific publications of 2020 which included zebrafish in their studies. This review will cover an article published in Nature Communications on January 30th, 2020: Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair1.This article challenges the current model of scarring after a heart attack and implicates macrophages, a type of white blood cell of the immune system, as direct contributors to collagen deposition during this process.Heart attack and heart failureScarring process after a…

Comments Off on Zebrafish to study a broken heart: macrophages’ implication in scar formation after a heart attack